How To Use Antimetabolite In A Sentence
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Methotrexate is an antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases.
PLoS ONE Alerts: New Articles
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The class of anticancer drugs that has been developed to interfere with aspects of nucleotide metabolism is known as the antimetabolites.
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With the latter therapy, once patients are weaned from steroids, the purine antimetabolite is continued for an indefinite period while the physician monitors white blood cell count and liver enzymes.
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This suggested that other enzymes might also recognize such a side chain as a pentose and that nucleoside analogs of this kind might have antimetabolite properties.
Nobel Lecture The Purine Path To Chemotherapy
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In 1940, Woods and Fildes (1,2) had put forth the antimetabolite theory to explain the action of sulfonamides on bacteria, suggesting that the sulfonamides interfered with the utilization of a necessary nutrient, para-aminobenzoic acid.
Nobel Lecture The Purine Path To Chemotherapy
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Antimetabolite: Substance that competes with, replaces, or inhibits a specific compound within a cell, whose functioning is thereby disrupted.
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Contributors Mary Relling did pharmacological studies of antimetabolites and identified their relation with risk of brain tumour.
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Therefore, acyclovir is transformed into its corresponding nucleotide which is the active antimetabolite and the growth of the virus is inhibited (Figure 3).
Physiology or Medicine 1988 - Press Release
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Learn about the research that led to the use of the antimetabolite drugs 6-mercaptopurine
The Spark of Yahoo!
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Most forms of gout can be treated by administering the antimetabolite, allopurinol.
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Antimetabolites are used to decrease the likelihood of fibrosis and scar formation in blebs and to increase the success rate of infiltration.
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Methotrexate is currentlythe only antimetabolite approved by the FDA as a treatment for psoriasis.
Psoriasis Guru » Blog Archive » How Does Methotrexate Work?
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Methotrexate Toxicity - antimetabolite/antifolate for cancer/autoimmune disease
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They prevented rabbits from producing antibody against human serum albumin by treating them for two weeks with the antimetabolite, 6-Mercaptopurine.
Joseph E. Murray - Nobel Lecture
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We have modified the recently completed St Jude protocol to withhold systemic antimetabolites during radiotherapy.
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The major categories are alkylating agents, antimetabolites, plant alkaloids, anti-tumor antibiotics, and steroid hormones.
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When this process is allowed to proceed normally it is also called “metobolizing,” somethotrexate is also called an “antimetabolite.”
Psoriasis Guru » Blog Archive » How Does Methotrexate Work?
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This protocol differed from previous protocols, in that more intensive systemic antimetabolite therapy was given before and during radiotherapy.
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Therefore, acyclovir is transformed into its corresponding nucleotide which is the active antimetabolite and the growth of the virus is inhibited (Figure 3).
Physiology or Medicine 1988 - Press Release
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Clofarabine, a type of drug called a purine nucleoside antimetabolite, works by blocking the production and repair of DNA, the building blocks of genes.
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Drugs such as alkylating agents, antimetabolites, anticonvulsants, chlorothiazide diuretics and estrogens can inhibit platelet production by suppressing megakaryocyte production. (2,3)
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In 1940, Woods and Fildes (1,2) had put forth the antimetabolite theory to explain the action of sulfonamides on bacteria, suggesting that the sulfonamides interfered with the utilization of a necessary nutrient, para-aminobenzoic acid.
Nobel Lecture The Purine Path To Chemotherapy
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Methotrexate is an antimetabolite that, apart from its use in malignant disorders, is taken orally in low doses for the control of conditions such as rheumatoid arthritis and psoriasis.
