How To Use Azido In A Sentence
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In 1986, a drug known as azidothymidine was identified by NCI researchers as inhibiting HIV activity in laboratory studies.
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The FDA approves AZT (azidothymidine), the first antiviral agent to treat AIDS.
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The frontier orbital is mainly formed by atomic orbitals of azido group, so it is the most reactive part of the molecule.
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The frontier orbital is mainly formed by atomic orbitals of azido group, so it is the most reactive part of the molecule.
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Extensive genetic screening allowed the team to target the azido probes efficiently.
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To apply their copper-free click chemistry to living mice, Bertozzi and her group delivered azides to the surfaces of target cells within the mice via a metabolic precursor, then labeled select glycans (those that bore corresponding azido sialic acids) by covalent reaction in vivo with a panel of cyclooctyne-FLAG peptide conjugates.
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Several analogs are used to interfere with the replication of HIV, such as AZT (azidothymidine) and ddI (dideoxyinosine).
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In general, reasonably high molecular weight azides are OK to handle (e.g., the early anti-HIV drug azidothymidine).
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III) - based metal-organic frameworks with engineered cores and surfaces, as well as imaging properties, function as superior nanocarriers for efficient controlled delivery of challenging antitumoural and retroviral drugs (that is, busulfan, azidothymidine triphosphate, doxorubicin or cidofovir) against cancer and AIDS.
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Because azido has a unique vibration frequency that is sensitive to its surroundings, the team was able to use the spectroscopic data to confirm structural changes rhodopsin undergoes in light versus dark.
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They then confirmed the presence of azido with fourier transform infrared (FTIR) difference spectroscopy, which measures stretching frequencies of the atoms in the amino acids that make up a protein.
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III) - based metal-organic frameworks with engineered cores and surfaces, as well as imaging properties, function as superior nanocarriers for efficient controlled delivery of challenging antitumoural and retroviral drugs (that is, busulfan, azidothymidine triphosphate, doxorubicin or cidofovir) against cancer and AIDS.
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Although the sulfated maitake fraction resembled the anti-HIV potency of AZT (zidovudine, formerly azidothymidine), it was not considered a promising treatment because of potential cellular toxicity in vivo.
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* Hang & Ploegh describe azido-E-64, a cell permeable activity based-probe that provided insight into how the pathogen Salmonella eludes destruction by the immune system.
Science Press Releases
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The three-nitrogen-atom azido is an especially good probe for three reasons: In contrast to other tags, azido does not exist naturally in mammals, which makes it easier to "see," or distinguish from other molecules in the cell; it is small enough to not interfere with a protein's normal functioning; and it has chemical properties that make it a good handle on which to hang other molecules, like fluorescent probes.
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