NOUN
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a mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system
the brain was protected from the large molecules of the virus by the blood-brain barrier
How To Use blood-brain barrier In A Sentence
- This agent crosses the blood-brain barrier and thereby reverses both central and peripheral effects of the abused anticholinergic drug.
- Aboody and her colleagues were the first to demonstrate in 2000 the inherent propensity of neural stem cells to home in on invasive tumor cells, also known as tropism, even migrating from the opposite side of the brain or across the blood-brain barrier. PhysOrg.com - latest science and technology news stories
- Another herb—red velvet bean plant—is used widely in Indian Ayurvedic medicine and contains L-dopa, which is converted to dopamine once it crosses the blood-brain barrier and might be used to treat Parkinson’s disease in higher doses. You Staying Young
- The body has lots of different barriers – blood-brain barrier, the skin, the lining of the gut , the placenta – and it may be that this mechanism works in some of these barriers.
- Recent work is again focused on the vascular changes as a basis of the breakdown of the blood-brain barrier that precedes the inflammation and demyelination in a multiple sclerosis plaque.
- The active transport mechanism for methylfolate across the blood-brain barrier strictly limits the entry of the vitamin, perhaps for reasons concerned with the excitatory properties of folic acid.
- A prerequisite for invasiveness is the ability of pneumococci to transmigrate and to disseminate through the epithelial and endothelial layers and to breach the blood-brain barrier.
- The clinical manifestations of hypertensive encephalopathy are due to increased cerebral perfusion from the loss of blood-brain barrier integrity, resulting in exudation of fluid into the brain.
- Here, using molecular modeling and in vitro and in vivo studies, we show (1) xenon is a tPA inhibitor; (2) intraischemic xenon dose dependently inhibits tPA-induced thrombolysis and subsequent reduction of ischemic brain damage; (3) postischemic xenon virtually suppresses ischemic brain damage and tPA-induced brain hemorrhages and disruption of the blood-brain barrier. Naturejobs - All Jobs
- Patients with frequent relapses often exhibit new lesions after enhancement with gadolinium, indicating focal breakdown of the blood-brain barrier.
