How To Use Chloroquine In A Sentence
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Protective measures: CDC recommends that travelers to areas of risk undertake chemoprophylaxis with chloroquine in addition to personal protective measures.
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Doctors treat malaria by using anti-malarial drugs, such as chloroquine or quinine.
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Roughly one-third (1808) had taken hydroxychloroquine for some period of time during the study, with duration of treatment averaging 3.1 years.
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Chloroquine resistance in P. falciparum may be multigenic and is initially conferred by mutations in a gene encoding a transporter (PfCRT) (13).
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The fear is that like chloroquine, an older class of antimalarial drug that has lost its power, artemisinin will be rendered useless through the emergence of resistant parasites.
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The antimalarial drug chloroquine practically prevents formation of this hematin under the conditions used.
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The antimalarial drug chloroquine practically prevents formation of this hematin under the conditions used.
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A change in chemotherapy is likely to have played a substantial role - until 2004, chloroquine alone was mainly used but as parasite resistance to this drug had increased to high levels, the first-line treatment of choice became sulphadoxine plus pyrimethamine (SP) combined with chloroquine, from early 2005 onwards.
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Malaria parasites highly resistant to chloroquine and pyrimethamine spread from Asian origins to Africa, at great cost to human health and life.
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So we combine it with established treatments such as chloroquine, mefloquine and the like.
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After more than a decade-and-a-half-long search, researchers have identified the gene that makes the most deadly malaria parasite resistant to chloroquine, the former mainstay, low-cost antimalarial drug.
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Doctors treat malaria by using anti-malarial drugs, such as chloroquine or quinine.
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Quinine formed the basis for synthesising the commonly used antimalarial drugs, chloroquine and mefloquine.
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Hydroxychloroquine is the most widely used; its effectiveness was studied in combination with quinacrine, another antimalarial drug.
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In many areas of Africa, chloroquine-resistant malaria is present and chemoprophylaxis is recommended for travelers especially when biking around the countryside.
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Quinine formed the basis for synthesising the commonly used antimalarial drugs, chloroquine and mefloquine.
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Overall, the hazard ratio for incident diabetes among patients who had taken hydroxychloroquine was 0.62% compared with those who had never taken it (95% confidence interval, 0.42 – 0.92).
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Chloroquine-related ototoxicity is considered to be rare.
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Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance.
The Edge of Evolution
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The cheapest antimalarial drug, chloroquine, is rapidly losing its effectiveness in almost all countries where malaria is endemic.
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Doctors treat malaria by using anti-malarial drugs, such as chloroquine or quinine.
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For many years the treatment of malaria in Africa has relied on chloroquine, sulfadoxine combined with pyrimethamine, and quinine, with the latter being used mainly to treat severe cases.
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During the Vietnam War, however, despite research to find better antimalarial drugs or a vaccine, chloroquine-resistent falciparum malaria from Southeast Asia threatened the U.S. armed forces.
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The situation is becoming more difficult because the most widely used antimalarial drug chloroquine is losing its effectiveness.
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On the other side of the equation, one of the biggest reasons for the increasing incidence of malaria has been the growing resistance of the malaria parasite to the main anti-malarial drug, chloroquine.
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Overall, the hazard ratio for incident diabetes among patients who had taken hydroxychloroquine was 0.62% compared with those who had never taken it (95% confidence interval, 0.42 – 0.92).
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MMV supports Pfizer's AZCQ clinical trial for intermittent preventive treatment of malaria in pregnant women Malaria Venture (MMV) entered into an agreement for the development, access and delivery of a fixed-dose combination treatment consisting of azithromycin dihydrate (AZ) and chloroquine phosphate (CQ) for the Intermittent Preventive Treatment of in pregnancy (IPTp).
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