NOUN
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(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity
genes were formerly called factors
How To Use cistron In A Sentence
- Similarly, a Cre-expressing plasmid or adenovirus was employed to remove three or four copies of a polycistronic vector from the genome of mouse iPSCs BioMed Central - Latest articles
- A number of studies have recently demonstrated the advantage of using polycistronic vectors for iPSC generation. BioMed Central - Latest articles
- A feasible way to decrease the risk of insertional mutagenesis is to combine the reprogramming factors into a single polycistronic vector by inserting a 'self-cleaving' 2A peptide or an internal ribosome entry site (IRES) sequence between two consecutive open reading frames. BioMed Central - Latest articles
- Among others, many prokaryotic messages are polycistronic, few eukaryotic. Uncommonly Dense blows common descent. - The Panda's Thumb
- We find mir-424 and mir-503 are derived from a polycistronic precursor mir-424-503 that is under repression by the MLL-MLLT3 leukemogenic fusion. Naturejobs - All Jobs
- If we propose that these regulate cistronic activity by their binding of proteins *like* transcription factors and cis/trans factors, *and* their binding of RNA sequences let us regard these too as transcription factors potentially with their own point mutations. It's more than genes, it's networks and systems - The Panda's Thumb
- Notably, these studies demonstrated that somatic cells carrying a single proviral copy of the polycistronic cassette can be reprogrammed to pluripotency, substantially reducing genomic modification of the target cell. BioMed Central - Latest articles
- ….then there is considerable scope to modulate the expression of the cistronic genome without any significant alteration of coding sequences. It's more than genes, it's networks and systems - The Panda's Thumb
- (CB) in prostate cancer was carried out using single and bi-cistronic siRNA-expressing constructs. Naturejobs - All Jobs
- Alternative initiation strategies by ribosomal frameshifting and leaky scanning enable polycistronic translation of the cap-dependent viral transcript. BioMed Central - Latest articles
