[
US
/ˈkɫoʊzəˌpaɪn/
]
NOUN
- an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effects
How To Use clozapine In A Sentence
- This registry provided a good database about people who had suicided while on clozapine versus those who had discontinued clozapine.
- Clozapine was first synthesized in 1958 as one of over 1900 tricyclic compounds with a structural similarity to imipramine.
- Currently a clozapine plasma concentration above 350 ng/ml appears to have the greatest potential benefit.
- Could early lawsuits against antipsychotics have had a stifling effect on developing clozapine?
- Examples of surveillance programmes being written into drug licensing decisions include clozapine and alosetron.
- Our analysis suggests that antipsychotic drugs other than clozapine may be associated with myocarditis and cardiomyopathy.
- The term ‘atypical’ was originally used to describe drugs that in animal models predict antipsychotic effects but do not produce catalepsy, most notably clozapine.
- The charge-transfer(CT)complex formed between clozapine as the donor and 7,7,8,8Tetracyanoquinodimethane(TCNQ)as the acceptor in acetone has been studied by spectrophotometric method.
- One drug, clozapine, is associated with reducing suicidal behaviour.
- This finding is clinically significant since it explains why many patients relapsed after being directly switched from clozapine to risperidone.
