How To Use Guanine In A Sentence
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We have evaluated selected molecular interactions of nucleobases in the simulated structures to obtain further insight in similarities and differences between the ability of guanine and inosine to form quadruplexes.
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Of the four bases that make up DNA - adenine, thymine, cytosine and guanine - only cytosine has the potential to be methylated in humans and most mammals.
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There are four types of nucleotides in DNA, each containing one of four bases - adenine, guanine, cytosine, or thymine.
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In DNA the bases pair to form a ladder-like structure, with adenine paired with thymine and guanine with cytosine.
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Each nucleotide unit is composed of a sugar, a phosphate, and one of four bases, adenine, cytosine, guanine, or thymine.
Spider Bones
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The nitrogen-containing units are the bases: adenine, cytosine, guanine, and uracil.
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A competitive pathway also converts 6-MP to its cytotoxic 6-thioguanine nucleotides (6-TGNs) that are associated with bone marrow suppression (leukopenia, neutropenia, thrombocytopenia).
Clinical studies: IBD treatment safety
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On single-stranded oligonucleotides, all the guanines are oxidized to the same extent.
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A number of catabolic enzymes were known: nucleases, nucleotidases, nucleosidases, deaminases (for guanine, adenine, adenosine, and adenylic acid), xanthine oxidase and uricase.
Nobel Lecture The Purine Path To Chemotherapy
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She had used the base pairs of the DNA --- combinations of pairs of four nucleotides called adenine, guanine, cytosine, and thy mine -- to encode her message.
Delta Search
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Apart from that, however, they would exhibit exactly the same coordination of the ions as in the channel of the guanine quadruplex as the electronic structure and molecular electrostatic potential of inosine and guanine are similar.
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The purines adenine and guanine are constituents of DNA.
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Life-threatening ways and assuming have supported observed as linkages of thioguanine-induced granulocytopenia and thrombocytopenia.
Wii-volution
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There are four DNA bases: adenine, cytosine, guanine, and thymine (A, C, G, and T).
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Thioguanine later found its main utility in the treatment of acute myelocytic leukemia in adults, in combination with cytosine arabinoside.
Nobel Lecture The Purine Path To Chemotherapy
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The nucleotide elements of DNA are adenosine, guanine, cytosine, and thymine, abbreviated A, G, C, and T, respectively.
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These symbols represent the four basic chemical letters, or bases, the body uses to form DNA--guanine, cytosine, adenine and thymine.
Gene Machine
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However, the efficiency of this process is low because the positive charge from the guanine radical cation also migrates to the solvent.
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For 40 years, efforts to understand the prebiotic synthesis of the ribonucleotide building blocks of RNA have been based on the assumption that they must have assembled from their three molecular components: a nucleobase (which can be adenine, guanine, cytosine or uracil), a ribose sugar and phosphate.
Convincing Evidence for God
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Causes and effects The structure of thalidomide is similar to that of the DNA purine bases adenine and guanine.
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This work, carried out between 1882 and 1906 showed that various substances, little known at that time, such as adenine, xanthine, in vegetable substances, caffeine and, in animal excrete, uric acid and guanine, all belonged to one homogeneous family and could be derived from one another and that they corresponded to different hydroxyl and amino derivatives of the same fundamental system formed by a bicyclic nitrogenous structure into which the characteristic urea group entered.
Emil Fischer - Biography
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This view was reinforced by the elucidation of Z DNA and Z RNA structures, where the syn purines are mostly guanines.
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All three enzymes showed a marked preference for adenine over guanine nucleotides.
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The genetic code refers to the sequence of nucleotides (such as adenine, thymine, guanine and cytosine, or A, C, T and G) that serve as the instructions for making amino acids, the building blocks of life.
Scientific American
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The derivatives of purine are called adenine and guanine, and the derivatives of pyrimidine are called thymine, cytosine and uracil.
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This oxidizing process leads to the formation of a guanine radical cation, similar to that formed by DNA photoionization which may be considered as the main intermediate in DNA oxidation.
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The derivatives of purine are called adenine and guanine, and the derivatives of pyrimidine are called thymine, cytosine and uracil.
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The film's name comes from the initials of the four DNA bases of our genetic code: guanine, adenine, cytosine and thymine.
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The film's name comes from the initials of the four DNA bases of our genetic code: guanine, adenine, cytosine and thymine.
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Among the possible geometries, tetraplexes are very stable structures in which the four strands are held together via repetitive guanine tetrads.
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The adenosine base frequency is represented by gray rhombs, cytosine frequency by black rectangles, guanine frequency by gray triangles, and thymine frequency by black circles.
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The four become cytosine, guanine, adenine, and thymine, and the quantum forces that maintained the rest of universe sit on the sidelines while life take center stage.
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The strands consist of sugar and phosphate groups, the sugars being attached to a base - adenine, thymine, guanine, or cytosine.
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Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines.
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Basically, there are three major chemicals that the tongue detects as being flavorful: inosine monophosphate (IMP), guanine monophosphate (GMP), and glutamate.
April 2005
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However, unexpectedly, the guanine analog, acyclovir (acycloguanosine), was over 100 times as active as the diamino compound
Nobel Lecture The Purine Path To Chemotherapy
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She was treated with a chemotherapeutic regimen that included daunorubicin, cytosine, and thioguanine.
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I realized that I could use a simple quilt block to represent each of the four bases in DNA: cytosine, guanine, adenine, and thymine.
Boing Boing
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In DNA the bases pair to form a ladder-like structure, with adenine paired with thymine and guanine with cytosine.
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The nitrogen-containing units are the bases: adenine, cytosine, guanine, and uracil.
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Even since 1776 when Scheele found uric acid in urinary calculus, several substances closely related to it such as xanthine, adenine and guanine, etc. have been detected in animal secretions.
Nobel Prize in Chemistry 1902 - Presentation Speech
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This lead to the loss of antitumor activity, with the exception of the 2-amino-6-mercapto derivative, thioguanine, which we had previously found to have strong antimetabolic activity.
Nobel Lecture The Purine Path To Chemotherapy
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The nitrogen-containing bases are adenine, thymine, cytosine, and guanine; these names are used to identify the nucleotides.
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The inverted repeat sequences of the guanine-rich 5'-half are expected to have a higher potential of forming the hairpin triplex.
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Earlier it was generally accepted that guanine and other similar substances originated from the protein molecule and Miescher thought that these bodies perhaps arose from protamine, while Piccard put forward the idea that
Albrecht Kossel - Nobel Lecture
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These bases can be chemically modified in a number of ways, including by alkylation, in which an alkyl group (or "adduct") is transferred onto a guanine base.
Innovations-report
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Furthermore, although Powner and colleagues 'synthetic sequence yields the pyrimidine ribonucleotides, it cannot explain how purine ribonucleotides (which incorporate guanine and adenine) might have formed.
Convincing Evidence for God
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It is a methyl guanine which fools the virus into ‘thinking’ it is a cyclic sugar guanosine it needs for growth.
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The sugar in DNA is deoxyribose while the bases are adenine, guanine, cytosine and thymine.
Physiological chemicals
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The technology at the time required that DNA be cut up into tiny pieces, transferred into bacteria and then put into machines that figured out the genetic code by sorting, by length, the letters of the genetic code: A, T, G and C, also known as adenine, thymine, guanine and cytosine.
The New, Fast Gene Machine
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We found that diaminopurine arabinoside (ara-DAP) was deaminated to guanine arabinoside in mice and that the guanine derivative
Nobel Lecture The Purine Path To Chemotherapy
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Isochores were defined as long genomic segments that are fairly homogeneous in their guanine and cytosine composition.
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This work, carried out between 1882 and 1906 showed that various substances, little known at that time, such as adenine, xanthine, in vegetable substances, caffeine and, in animal excrete, uric acid and guanine, all belonged to one homogeneous family and could be derived from one another and that they corresponded to different hydroxyl and amino derivatives of the same fundamental system formed by a bicyclic nitrogenous structure into which the characteristic urea group entered.
Emil Fischer - Biography
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It therefore seems that both DNA structure and hydrogen bonding to guanine contribute towards sequence recognition.
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The C - 8 position of guanine in DNA is the major site of reaction of the potent electrophile acetoxy-IQ, which forms a nitrenium ion, by heterolytic loss of the acetoxy group, as the ultimate DNA-reactive species.
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We found that diaminopurine arabinoside (ara-DAP) was deaminated to guanine arabinoside in mice and that the guanine derivative
Nobel Lecture The Purine Path To Chemotherapy
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The derivatives of purine are called adenine and guanine, and the derivatives of pyrimidine are called thymine, cytosine and uracil.
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We modeled the modified complex by replacing the guanine in the native structure with coumarin and allowing rotation about the glycosidic bond.
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Adenine can be formed from ammonia and hydrogen cyanide, as can guanine.
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Two of the named four bodies, adenine and guanine, belong to a group of chemical compounds which today are usually included under the name of alloxan derivatives or purine derivatives.
Albrecht Kossel - Nobel Lecture
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During DNA replication, DNA polymerase incorporates unmethylated cytosine opposite to guanine, leading to an overall reduction in methylation of DNA.
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There are four DNA bases: adenine, cytosine, guanine, and thymine (A, C, G, and T).
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These bases are adenine, cytosine, guanine and thymine and can be represented as A, C, G, and T, respectively.
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Furthermore, although Powner and colleagues 'synthetic sequence yields the pyrimidine ribonucleotides, it cannot explain how purine ribonucleotides (which incorporate guanine and adenine) might have formed.
Convincing Evidence for God
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Indeed, guk1 and hpt1 mutants share several phenotypes (adenine derepression, purine excretion, and 8-azaguanine resistance).
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It therefore seems that both DNA structure and hydrogen bonding to guanine contribute towards sequence recognition.
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They are made up of tightly coiled, double strands of DNA linked in a ladder-like structure with four nitrogenous chemicals: adenine, cytosine, guanine and thymine.
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The nitrogen-containing units are the bases: adenine, cytosine, guanine, and uracil.
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The purines adenine and guanine are constituents of DNA.
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A further possible pathway of guanine quadruplex formation has also been proposed that is essentially a triplex dissociation process.
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He was diagnosed with acute monoblastic leukemia (AML-MSa) and subsequently underwent induction therapy with daunorubicin, 6-thioguanine, and cytosine arabinoside.
