How To Use Monogenic In A Sentence
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Cystic fibrosis is one of the most common monogenic disease and was chosen for gene-targeting studies by Smithies and his co-workers [53, 54].
The 2007 Nobel Prize in Physiology or Medicine - Advanced Information
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Recent advances in genetics such as the identification of the responsible genes for several forms of Maturity Onset Diabetes of the Young (MODY), now referred to as monogenic diabetes, have established precedents linking specific drug therapies to defined subtypes of diabetes patients," said Robert Smith, MD, of Brown University in Providence, R.I. and co-author of the statement.
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The inheritance of apospory has been investigated in a considerable number of plant species and, remarkably, is always inherited as a monogenic dominant trait.
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Classical genetics of human disease deals with monogenic disorders in which a single mutation in a single gene is causatively related to the phenotype.
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We didn't need the gene sequence to find most monogenic disorders.
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Monogenic and polygenic inheritance of adult resistance under controlled and field conditions has been reported in the literature.
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Monogenic control was also found for spiny versus spineless, with the spiny trait being completely or partially dominant.
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Another difficulty when working with agronomically relevant traits is that many quantitative traits are not inherited in a monogenic manner but are controlled by multiple genes.
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Prenatal tests for some of these single-gene maladies -- known as monogenic diseases -- are available today, but they require a needle to be inserted into the mother's womb and therefore carry a small risk of miscarriage.
Prenatal Test Has Promise, Study Shows
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These so-called monogenic conditions — diseases like hemochromatosis (where the body absorbs too much iron) or Huntington's disease — are easy to research, because the associations are pretty much binary.
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A monogenic inheritance is unlikely when considering the low prevalence and high frequency of the suspected disease locus.
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Major malformations were neural tube defects and monogenic traits, syndromes, and sequences, and minor defects were anomalies such as syndactyly of the second and third toes.
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We didn't need the gene sequence to find most monogenic disorders.
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A large number of genes have been described and assigned to specific locations among the 12 chromosomes, and numerous monogenic mutants are available.
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Results: The true pattern in the palmar hypothenar area showed the pedigree character of monogenic trait in 5 families.
