How To Use Mucosal In A Sentence
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More severe inflammation of the mucosa is readily evident as erythema, intramucosal hemorrhage, exudate, or ulceration.
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These results suggest the involvement of platelet activating factor in the endothelin induced fibrinolytic activation and subsequently developed mucosal haemorrhagic lesion.
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It has also been proposed that H pylori ammonia production will lead to mucosal damage by denaturing the protective mucus layer.
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This is the first reported attempt to evaluate the mucosal availability of 5-ASA after different oral preparations.
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As the disease progresses, the mucosal erosions coalesce to linear ulcers that undermine remaining mucosa.
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Ferrous and ferric iron catalyze the formation of reactive oxygen metabolites, which may mediate mucosal injury.
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In summary, our data show that the absence of PlGF strongly inhibits mucosal intestinal angiogenesis in acute colitis, which is associated with an early increase in intestinal epithelial hypoxia and aggravation of the course of the disease.
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Pathology in chronic cholecystitis reveals low grade chronic inflammatory changes with muscle hypertrophy and submucosal lymphocytic and plasma cell infiltration.
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Mild forms of cleft palate include submucosal clefts, pharyngeal incompetence and bifid uvula.
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The colon can be identified by its size and the absence of mucosal folds and villi; the inner surface is smooth.
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Thermal balloon therapy is contraindicated in patients with a submucosal myoma or bicornate or septate uterus.
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It is possible that an increased mucosal blood flow due to the inflammation perse can contribute to increased absorption.
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However, because the disease usually begins in the second decade of life, these studies may not help our understanding of the pathogenesis of new or early mucosal lesions.
IBD clinical studies: diagnostic testing
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They reduce mucosal oedema and bronchial hyperreactivity thus relieving acute symptoms and preventing structural damage to the lungs.
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In circumcised males only the distal penile urethra is lined with a mucosal epithelium.
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No cutaneous, ocular, anal, rectal, nasal, or oral mucosal lesions were demonstrated on thorough physical examination.
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Objective : To explore and regularities of diagnose method for oral mucosal stria diseases.
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Up to 70 percent of patients with lichen planus may have mucosal involvement.
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These reflexes are initiated by the excitation of duodenal mucosal chemoreceptors to acid, fats, and osmotic pressure in the luminal contents.
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Nevertheless, These findings suggest that chronic psychological stress can be an initiating factor in intestinal inflammation by impairing mucosal defenses against luminal bacteria ....
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Either polyunsaturated fatty acids enhanced mucosal resistance or the oleic acid supplement weakened the defensive mechanisms.
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Due to low amount of IgA in mucosal fluids, a high sensitive sandwich ELISA assay was set; sensitivity was enhanced by milk-based overcoating buffer and by a two-step biotin-streptavidin signal amplification.
Elites TV
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Colonic mucosal biopsies of tissue from CD patients found abnormally low levels of zinc from uninflamed but not from inflamed tissue.
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Resufts: All of buccinator myomucosal flaps survived without infection, hematoma, parotid duct injury, facial nerve injure or restriction of opening motion.
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At the same time, the inflammation causes gaps to open between the mucosal cells, allowing the wholesale penetration of toxins, undigested food particles and other debris into the bloodstream.
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Our patient presented with obstructive jaundice and had a large mucosal mass located in the midportion of the common bile duct.
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Virosomes are lipidic vesicles derived from influenza virus membrane that are non-replicative antigen carriers which possess intrinsic systemic and mucosal adjuvant properties.
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There is a disproportionate reduction of serous acini of the submucosal glands, which contain lysozyme, lactoferrin, and an antiprotease of small molecular weight.
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MEN2B is diagnosed clinically by the presence of mucosal neuromas of the lips and tongue, as well as medullated corneal nerve fibers (a finding seen on eye evaluation by an ophthalmologist), distinctive facial features with full lips, particular physical characteristics such as slender body habitus, and medullary cancer of the thyroid (MTC).
Multiple Endocrine Neoplasia Type 2
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The alimentary canal is supplied with rich plexuses beneath the epithelium, often as a superficial plexus in the mucosa and a deeper submucosal plexus.
VIII. The Lymphatic System. 1. Introduction
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Likewise, an intense microcirculation of intestinal contents across the mucosal surface must occur, for the stirring of the unstirred layer at this surface is essential for the optimal absorption of nutrients.
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These results suggest the involvement of platelet activating factor in the endothelin induced fibrinolytic activation and subsequently developed mucosal haemorrhagic lesion.
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This position, supported under the P30 mechanism, is designed to attract appropriately trained postdoctoral fellows or junior investigators (no previous tenure track appointment) to explore one or more of the following research areas: (1) interplay of innate/adaptive immune systems and bioflims, possibly using germfree/gnotobiotic models; (2) mucosal vaccinology; or (3) autoimmunity.
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The tumor thickness was measured with an ocular micrometer from the most superficial layer of mucosal epithelium, ulcer base, or granular layer of squamous mucosa, to the deepest invasive tumor cell.
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adenomatous polyps are visible protrusions that can develop on the mucosal surface of the colon or rectum
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Partial or total gastrectomy was performed in all patients, except in patient 6, who underwent removal of a submucosal nodule covered by apparently normal mucosa.
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The lesion appeared to be submucosal with an intact submucosa and muscularis propria interface.
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Gastro-oesophageal reflux disease is defined as symptoms or mucosal damage resulting from the exposure of the distal oesophagus to refluxed gastric contents.
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• Sperm degenerate 48hours after ejaculation • May survive up to 4 days in female genital tract (submucosal)
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Here we report significantly increased SPAK expression levels in hyperosmotic environments, such as mucosal biopsy samples from patients with Crohn's disease, as well as colon tissues of C57BL / 6 mice and Caco2-BBE cells treated with hyperosmotic medium.
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In mucosal edema the surface has a granular appearance or appears to be ‘dry’ so that it does not glisten.
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They are probably sensory fibers of the thoracolumbar system, possibly modulating the pain of esophageal mucosal inflammation.
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The inflammatory response to viral-induced bronchiolitis includes bronchial obstruction, increased airway secretion, mucosal edema, and infiltration of inflammatory cells including eosinophil granulocytes.
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Inflammatory bowel disease mucosal biopsies have specialized lymphokine mRNA profiles.
The Autoimmune Epidemic
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Mucosal erythroplasia, not leukoplakia, is the earliest sign of oral cancer.
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It runs the entire length of the bronchial tree and forms an extensive submucosal bronchial plexus.
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Mucosal atrophy may result when dietary sources of fatty acids are lacking or when the fecal stream is diverted by an ileostomy or colostomy.
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Biopsies of the pharynx, performed after radiotherapy, showed infiltration of small lymphocytes, plasmacytes, and neutrophils in the submucosal area.
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The temporal transition of a mucosal cell from a normal state to dysplasia and eventually carcinoma can be explained by the multistep theory of carcinogenesis.
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Patients should look cautioned against cardiovascular metformin antipsychotic intake, either mucosal or chronic, when having glyburide/metformin hydrochloride, since continuation potentiates the hours of toxicity hydrochloride on word metabolism.
Wii-volution
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Protect existing wounds, skin rashes or lesions, conjunctivae and mucosal surfaces from all blood and body fluids.
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Cryptosporidium is a cause of chronic diarrhoea and a proximal small intestinal mucosal enteropathy in children without immune deficiency.
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Protrusion of tissue through the anus may be due to hemorrhoids, mucosal prolapse, polyps or other lesions.
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Although it is a benign inhabitant of mucosal surfaces in most individuals, it is a significant cause of infection when host or environmental factors are permissive.
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Bronchoscopic examination performed within 1 day or 2 days of menses disclosed multiple purplish-red submucosal patches bilaterally that bled easily when touched.
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Gastric and duodenal ulcers were noted to evolve from early superficial mucosal disease.
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Therapeutic trials include those with proton pump inhibitors, prokinetic agents, mucosal protectants, anticholinergics and low-dose antidepressants.
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An abnormal coagulation profile and raised portal pressure then tend to enhance longitudinal and circumferential expansion, resulting in submucosal dissection.
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Peutz-Jeghers syndrome (PJS) is a hereditary cancer syndrome identified by the presence of gastrointestinal polyps and altered pigmentation (freckling) of certain skin and mucosal areas.
Peutz-Jeghers Syndrome (PJS)
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On digital rectal examination, a submucosal tumor was palpated at the anorectal junction.
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According to this theory, an initial insult caused by an infective agent, drugs, or gluten may damage mucosal surface, leading to an autoimmune response with ongoing inflammation in susceptible individuals.
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Balloon supports precise delivery of submucosal needles
Medgadget
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Pathologic findings in fatal asthma include bronchial lumen occlusion by mucus, hyperplasia of submucosal glands, basement membrane thickening, and tissue eosinophilia.
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Nevertheless, These findings suggest that chronic psychological stress can be an initiating factor in intestinal inflammation by impairing mucosal defenses against luminal bacteria ....
More Stress, Depression & Health
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These studies show that mucosal metabolism can be assessed effectively using biopsy specimens without the need for epithelial cell purification.
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The sacculus rotundus of rabbits are a unique intestinal mucosal immune organ for rabbits and played an important role in the anti-infection immunity.
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Either polyunsaturated fatty acids enhanced mucosal resistance or the oleic acid supplement weakened the defensive mechanisms.
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Similarly it was not hydrolysed by mucosal homogenates from the small intestine of the rat.
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The ‘volcano sign’ described endoscopically is seen as a ‘vortical fold’ pattern on barium studies, which is the concentric ring appearance of the cecal mucosal folds as they approach the obstructed appendiceal orifice.
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In portal hypertensive gastropathy, the mucosa is friable and bleeding occurs when the ectatic vessels rupture and manifest as mucosal oozing.
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The normal mucosal biopsies in the remaining patients may have been due to random sampling.
Clinical studies: relationship between IBD and other conditions
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Abnormal vaginal microbiota could even be secondary to defective protection of the mucosal immune system.
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Underlying microscopic mucosal inflammation coexists with JRP and this may be a risk factor or possible etiology for the development of JRP.
Clinical studies: relationship between IBD and other conditions
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IL-6 production may be a marker of a predominant THELPER2 cells responses or implicate macrophages as important antigen-presenting cells in generating the early mucosal lesions in pediatric IBD patients.
IBD clinical studies: diagnostic testing
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What's interesting is that we're finding - and we've known this for a while, but we're beginning to appreciate it - that HPV plays a role in other 'mucosal' cancers.
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Several bullous mucosal lesions, devoid of typical viral cytopathic features, were present in a background of scant submucosal mononuclear inflammation.
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The study of gastric mucosal proliferation may have important clinical applications.
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It is characterized by crypt abscesses and ulcerations extending down to the muscularis and surrounded by prominent mucosal infiltrate of inflammatory cells.
IBD resources for professionals
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Peutz-Jeghers syndrome (PJS) is a hereditary cancer syndrome identified by the presence of gastrointestinal polyps and altered pigmentation (freckling) of certain skin and mucosal areas.
Peutz-Jeghers Syndrome (PJS)
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The dynamics and importance of H pylori reduced altered mucosal peptic activity is far from being clarified.
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The only mucosal protective drug being used, says Murray, is sucralfate (Carafate), and it is only effective for the glandular lining of the stomach and the duodenum, where ulcers and lesions are less likely to occur.
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Upper gastrointestinal endoscopy and colonoscopy were macroscopically normal and mucosal biopsy specimens were obtained.
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It has also been proposed that H pylori ammonia production will lead to mucosal damage by denaturing the protective mucus layer.
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The colon can be identified by its size and the absence of mucosal folds and villi; the inner surface is smooth.
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MEN2B is diagnosed clinically by the presence of mucosal neuromas of the lips and tongue, as well as medullated corneal nerve fibers (a finding seen on eye evaluation by an ophthalmologist), distinctive facial features with full lips, particular physical characteristics such as slender body habitus, and medullary cancer of the thyroid (MTC).
Multiple Endocrine Neoplasia Type 2
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Mucosal mast cells in the rat intestine are drastically affected by an infection with Nippostrongylus brasiliensis.
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We sought to determine if JRP are associated with histological mucosal inflammation and whether this predisposes the patient to inflammatory bowel disease (IBD).
Clinical studies: relationship between IBD and other conditions
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Reduction of the lumenal larvae and adult cyathostomes was in the high 90\% to 100\% range, but the variability against the mucosal stages would not make moxidectin the ideal drug to use for prevention of larval cyathostomosis in equines.
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The large mucosal surface of the bronchial tree is exposed constantly to inhaled antigens.
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I think of it as arising from pain fibers that are not mucosal but deeper in hollow organs or in solid masses.
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It is possible that an increased mucosal blood flow due to the inflammation perse can contribute to increased absorption.
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The smallest air-conducting vessels, the bronchioles, are distinguished by having no cartilage in their walls, no mucus cells in their epithelium, and few or no submucosal glands.
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Anticholinergics block muscarinic receptors on airway smooth muscle and possibly on submucosal gland cells.
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Objective: To summarize our experience on treatment of bronchopleural fistula through submucosal injection of sclerosing agent -1% polidocanol using flexible bronchoscope.
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These proteases are both endopeptidase and exopeptidase, and their combined action in the intestine leads to the production of amino acids, dipeptides, and tripeptides, all of which are taken up by enterocytes of the mucosal wall.
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Later, it would be diagnosed as a submucosal throat haemorrhage, but that was later.
Sinatra The Man Behind the Myth
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Hence, we postulated that adaptive cytoprotection maintains a physiological equilibrium between duodenal mucosal resistance and luminal acidity.
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If participants developed any mucosal or skin reaction, hypotension, upper or lower airway reaction, conjunctival reaction, or laryngeal edema during the challenge test, it was considered a positive response.
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By sigmoidoscopy, a submucosal ovoid polypoid mass measuring about 2 cm in greatest dimension was identified at 4 cm above the anal verge.
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Fig . 6 . Submucous myomas. The uterine cavityby myomas arise from the submucosal myometrium.
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These studies show that mucosal metabolism can be assessed effectively using biopsy specimens without the need for epithelial cell purification.
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(otorhinolarngologists) (type I-V cordectomies) comprise a vast range of procedures from simple vocal cord stripping or submucosal cordectomy (type I) through more extensive surgery
Yemen Observer
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Chiefly, the Cupid's bow was reconstructed with full-thickness skin excision, and the vermilion deficiency repaired with the mucosal flap from the lower lip.
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The Finnish study suggests that probiotics may be useful in preventing respiratory infections, a mucosal site not in direct contact with the site of colonisation by the probiotic.
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Our data are also consistent with observations in man that mucosal proliferation is increased in patients with large adenomas or cancer.
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They include skin and mucosal pigmentation, postural hypotension, weight loss, and hyperkalaemia.
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The cause of death was excessive infusion and absorption of normal saline during hysteroscopic ablation of submucosal leiomyoma for menorrhagia.
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The main step in the pathogenesis of actinomycosis is disruption of the mucosal membrane leading to suppuration and abscess formation.
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The surgical specimen consisted of the nasal septum and irregular, mucosal, polypoid tissues.
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The aim of the present study was to define the possible use of an adjuvant that could be used without conjugation, both by parenteral and mucosal immunization, to increase the immunogenicity of M protein.
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Inhibition of prostaglandin synthesis by NSAIDs is the major established mechanism by which NSAIDs render the gastric mucosa vulnerable to mucosal injury.
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Since diffusion through this layer is the rate-limiting step in the intestinal absorption of many nutrients, the mucosal muscle, by stirring this otherwise unstirred layer of fluid, may have a critical place in nutrition.
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We observed that hypoxia is a common event in the mucosal capillary blood of bronchial tumors.
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To investigate changes and clinical significance of gut mucosal barriers function damages following traumatic hepatorrhexis without hemorrhagic shock.
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A small proportion of patients with mucosal disease will have repeated relapses.
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First large animal model of peritoneal carcinomatosis from gastric cancer has been established by laparotomic orthotopic injection of VX2 cancer cells into the submucosal layer of the stomach, providing a more suitable model for surgical interventional studies.
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The aim of the approach is to reduce the risk of vaginal or anal transmission of the virus by killing or inactivating it, creating a barrier to mucosal cells or preventing the infection taking hold after it has entered the body.
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The MSU M Cell vaccine technology that has been licensed by LigoCyte is based on the targeting of mucosal M-cells using a protein isolated from reovirus.
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Alternatively, serum antibody may be transuded into tracheal secretion or reach mucosal surface in inflammatory exudates.
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Parameters for intestinal mucosal morphometry (number of villi, villous height, mucosal thickness) and number of mucous containing cells were determined.
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Afterwards the samples were stained with haematoxylin-eosin to evaluate the number of villi, villous height and mucosal thickness and with PAS to identify mucous containing cells.
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Other clinical signs which emerge include tachycardia (fast heart rate), lymphadenopathy (enlarged lymph nodes), and a petechial rash (a rash caused by bleeding into the skin), both on internal mucosal surfaces, such as in the mouth and throat, and on the skin.
Chapter 2
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Standard haematoxylin and eosin stained preparations were scored according to the inflammatory scale previously established for use in reservoir mucosal biopsy tissue.
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It seems possible that this material originates from rare mucosal endocrine cells expressing the gastrin gene.
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The endoscopic submucosal dissection (ESD) technique was used to remove a large lesion en bloc.
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Endothelin-1 in this range induced mucosal haemorrhagic changes in a dose dependent manner.
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“He died from an acute laryngeal fracture associated with massive submucosal hemorrhage and consequential asphyxiation.”
A Long Day for Dying
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Mucosal atrophy may result when dietary sources of fatty acids are lacking or when the fecal stream is diverted by an ileostomy or colostomy.
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An upper gastrointestinal tract endoscopy showed mucosal telangiectasia in the stomach and duodenal bulb.
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These results could suggest a prominent role of tissue type plasminogen activator in the pathogenesis of endothelin induced gastric mucosal damage.
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Some of the nodules were located in the submucosa beneath areas of mucosal ulceration, but did not show communication with or disruption of the mucosa.
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This inhalant, which is used as a smelling salt, is capable of causing caustic burns to the oral cavity if bitten or mucosal burns if inserted in the nose, due to the high content of ammonia.
Caustic Smelling Salts
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This protocol tested mucosal resistance to acid after mild irritation.
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Afterwards the samples were stained with haematoxylin-eosin to evaluate the number of villi, villous height and mucosal thickness and with PAS to identify mucous containing cells.
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In addition, there are several entirely new classifications: gastrointestinal carcinoids (neuroendocrine tumours) gastrointestinal stromal tumour upper aerodigestive mucosal carcinoma uterine sarcomas intrahepatic cholangiocarcinoma
THE MEDICAL NEWS
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Gastrin is the designation given to a family of protein hormones produced by the mucosal cells of the gastric antrum.
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First, under normal conditions, dietary histamine is degraded in the intestine by mucosal diamine oxidase enzyme; this prevents histamine's entry into the circulation.
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It is possible that such bioactive proteins may be distributed some distance away from the allergen-induced airway mucosal processes.
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The muscle fibers in the mucosal muscular layer are also longitudinal, oriented along the axis of the cylindrical organ.
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VX2 tumor was implanted into 36 New Zealand rabbits by 3 methods: laparotomic orthotopic injection of cancer cells into the submucosal layer of the stomach (Group A), laparotomic implantation of tumor tissue into the greater omentum immediately beneath the gastric antrum
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Establishment of a causal role for leukotrienes in the pathogenesis of mucosal damage has, however, remained elusive.
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Analysis of the anterior wall biopsy specimens showed none of the characteristic histopathological features of mucosal prolapse.
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GUPTA: Antillon used the technique new to the United States, endoscopic submucosal dissection, ESD.
CNN Transcript Mar 28, 2009
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These results suggest the involvement of platelet activating factor in the endothelin induced fibrinolytic activation and subsequently developed mucosal haemorrhagic lesion.
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Recurrent aphthae constitute the most common oral mucosal disease and affects up to 25% of the population.
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No mucosal involvement, blebs or bullae were apparent, and the patient gave no history of any recent use of external or internal agents that might explain the rash.
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This is the first reported attempt to evaluate the mucosal availability of 5-ASA after different oral preparations.
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Therefore we suggest that platelet activating factor should be considered as a global mucosal activity marker.
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Methods Endoscopic observation and mucosal biopsies graft through the terminal ileum enterostomy were carried out.
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A research team from Japan reported a case of a large lipoma, 50 mm in diameter, in the terminal ileum, which was completely removed by a combination of the so-called endoscopic unroofing technique and endoscopic submucosal dissection.
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Standard haematoxylin and eosin stained preparations were scored according to the inflammatory scale previously established for use in reservoir mucosal biopsy tissue.
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However, as with motility disorders, there is little correlation between symptoms and severity of duodenitis, and no relationship between treatment and improvement of mucosal appearance on endoscopy.
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Two weeks after submucosal cancer cells injection in Group A, ulcerative gastric cancer with peritoneal carcinomatosis showed typical VX2 tumor pathology, with widespread intraperitoneal metastatic nodules, bloody ascites and perspicuous pulmonary metastases.
BioMed Central - Latest articles
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Either polyunsaturated fatty acids enhanced mucosal resistance or the oleic acid supplement weakened the defensive mechanisms.
-
This is the first reported attempt to evaluate the mucosal availability of 5-ASA after different oral preparations.
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It was beyond the scope of this study to enquire into the way by which urethane inhibits mucosal repair processes.
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Nicotine is absorbed through the skin and mucosal lining of the mouth and nose or by inhalation in the lungs.
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The sensitivity of the assay is not great enough to detect the small quantity of pepsinogen known to be present in blood (presumably after direct absorption from gastric mucosal cells).
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The muscle fibers in the mucosal muscular layer are also longitudinal, oriented along the axis of the cylindrical organ.
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It has also been proposed that H pylori ammonia production will lead to mucosal damage by denaturing the protective mucus layer.
-
Multiple endocrine neoplasia type 2B (MEN2B) is characterized by an increased risk for medullary cancer of the thyroid (MTC), pheochromocytoma, mucosal neuromas (benign growths) of the lips and tongue, and distinctive physical characteristics, such as enlarged lips and slender body type.
Multiple Endocrine Neoplasia Type 2
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One of the advantages of this approach, Desai says, is that it may be applicable for delivering drugs to other part of the body as well, such as mucosal tissues like the insides of the nose, lungs, or vagina, where the surface cells are also coated with such cilia.
PhysOrg.com - latest science and technology news stories
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They cause localized hyperproliferations manifested most commonly as skin warts or as mucosal condylomata.
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Many drugs are used for the treatment of GERD such as omeprazole (a proton pump inhibitor) which is a widely used antiulcer drug demonstrated to protect against esophageal mucosal injury.
BioMed Central - Latest articles
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These include oral leukoplakia (white plaques) and erythroplakia (velvety, reddish mucosal lesions).
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These L4 then emerge on to the mucosal surface, migrate to the colon, develop to the adult stage.
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New advances in molecular epidemiology, host mucosal immunology, and antifungal treatment have, however, enlivened investigation into this common condition.
