How To Use Mutagenesis In A Sentence
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Thus, multiple rounds of mutagenesis are possible by switching the two resistance genes on and off.
The Scientist
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It has a wide cell tropism and remains extra-chromosomal, therefore minimising the risk of insertional mutagenesis.
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Evaluating the results of their experiments the Clemson researchers concluded: "Juice from strawberry, blueberry, and raspberry fruit significantly inhibited mutagenesis.
Slimming Strawberries For Weight Loss
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Plants for mutagenesis were the progeny of one pair of plants from this inbred population.
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In this way, ellagic acid effectively increases detoxification of carcinogens and reduces mutagenesis and tumourigenesis.
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Alteration of residues by site directed mutagenesis which are close to, or in contact, with the sugar result in variety of effects ranging from insoluble protein through inactive enzyme to little observable change.
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For example, SINES and LINES can cause insertional mutagenesis, hybrid dysgenesis, chromosomal rearrangements, etc.
Junk DNA, Junk Science, and The Onion Test - The Panda's Thumb
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An understanding of evolution as endogenous adaptive mutagenesis looks to "have many practical implications?
2008 June - Telic Thoughts
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In each mutagenesis reaction, the functionality of the resistance genes is reversed using a pair of "on/ off" oligonucleotides.
The Scientist
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A feasible way to decrease the risk of insertional mutagenesis is to combine the reprogramming factors into a single polycistronic vector by inserting a 'self-cleaving' 2A peptide or an internal ribosome entry site (IRES) sequence between two consecutive open reading frames.
BioMed Central - Latest articles
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X-ray mutagenesis led to the identification of dominant mutations altering the number of bristles.
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I'm not sure what you are referring to by 'known mycobacterial mutations', but the main polymerase responsible for induced mutagenesis in M. tuberculosis including antibiotic resistance following infection (DnaE2 – see Boshoff et al Cell.
Browsing the Latest Issue of Scientific American
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Transgenic mouse modelling has provided a new approach to study the various steps involved in spontaneous and induced mutagenesis in rodent somatic and germline tissues in vivo.
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Insertional mutagenesis is a method for identifying genes by using the integration of DNA as the mutagen , thereby facilitating the cloning of the mutated gene.
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Using synthetic analogs of lerisetron as molecular probes in combination with site directed mutagenesis, we have identified some of these interactions and have proposed a model of the lerisetron binding site.
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Additional studies such as mutagenesis of Ser112 of BAD
PLoS ONE Alerts: New Articles
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The FeLV-induced tumors are thought to be caused, at least in part, by somatically acquired insertional mutagenesis in which the integrated provirus may activate a proto-oncogene or disrupt a tumor suppressor gene.
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Such mutants have been generated by chemical mutagenesis, gene disruption, and antisense gene silencing.
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I'm not sure what you are referring to by 'known mycobacterial mutations', but the main polymerase responsible for induced mutagenesis in M. tuberculosis including antibiotic resistance following infection
Browsing the Latest Issue of Scientific American
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Using synthetic analogs of lerisetron as molecular probes in combination with site directed mutagenesis, we have identified some of these interactions and have proposed a model of the lerisetron binding site.
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This gives the appearance of directed mutagenesis because only revertant cells survive mutagenesis.
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While the purpose of early mutant isolations was mostly focused on the identification of auxotrophs, many of these early strains have been subjected to heavy mutagenesis.
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This calibrates the nucleotide mutation rate for two mutagenesis centers, implies significance criteria for positional cloning efforts, and provides working estimates of effective genetic target sizes for selected phenotypes.
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Yes, but site-directed mutagenesis is not the same as either evolution or ID – it's a special and limited case.
Creationism, defined
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Point mutations were created by oligonucleotide-mediated site-directed mutagenesis and confirmed by DNA sequencing.
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The experiment I referenced demonstrated (actually a series of experiments) that DNA damage in M. tuberculosis results in the induction of an SOS-regulated polymerase (DNAE2), which causes base substitution mutagenesis, that is, the experiment was set up so that the only drug resistant mutations that was scored was base substitution mutagenesis.
Browsing the Latest Issue of Scientific American
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HcRed1 was originally derived from a non-fluorescent chromoprotein that absorbs red light through mutagenesis to produce a weakly fluorescent obligate dimer having an absorption maximum at 588 nanometers and an emission maximum of 618 nanometers.
Archive 2005-10-01
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A lower intensity of mutagenesis can explain all observed revertants if each mutagenized cell has multiple copies of the lac operon.
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A new altered sites mutagenesis systems for the cloning DNA is described.
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To understand the role of the contact HLA-G residues in HLA-G recognition by NK cells we performed an extensive site-directed mutagenesis which is listed in HLA-G is markedly different from HLA-C and other selected MHC class I molecules in the contact residues between KIR and HLA-C.
PLoS ONE Alerts: New Articles
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In this work, saponified coconut oil was used as a chemical model to explain the behavior of amphiphilic molecules in biological systems related to their mutagenesis potential.
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The paper brief talks the drinking water's mutagenesis from organic pollution.
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DNA adduct formation is a critical event in mutagenesis and in the initiation of carcinogenesis.
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Similar arguments and requirements apply to mutants created by transposon mutagenesis.
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Cantankerous and rigid with old age, Morgan refused to give Muller full recognition for his theory of mutagenesis, which he regarded as a largely derivative observation.
The Emperor of All Maladies
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While transposon mutagenesis involves elaborate PCR screening, RNAi generates only gene-specific phenocopies of loss-of-function mutations and does not always cause a true null phenotype.
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I also started my first mutagenesis and began looking for touch-insensitive mutants.
Martin Chalfie - Autobiography
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Smith's work forms the basis for site-directed mutagenesis, a technique by which it is possible to change a specific amino-acid in a protein and thereby illuminate its functional role.
The Nobel Prize in Chemistry: The Development of Modern Chemistry
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Evidence that PP may play a dominant role in UV-induced transition mutagenesis has been obtained for bacteria and lambda phage.
