How To Use Plasminogen In A Sentence
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It produces an antifibrinolytic effect through the reversible blockade of lysine binding sites on plasminogen molecules.
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The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
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Blood flow can be restored if tissue plasminogen activator, or tPA, is administered soon after the stroke occurs.
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Murine monoclonal antibodies conjugated with plasminogen activators may be valuable for targeting the therapeutic agent to thrombus.
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The screening of human tissue plasminogen activator recombinant plasmid showed that the two methods can recognize the positive colones quickly and correctly.
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Just 42 patients in the recombinant tissue plasminogen activator trials were over 80, and only a few had lacunar strokes.
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Our results confirm that alcoholic ascites contains plasminogen activating activity.
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The broad spectrum serine protease plasmin is formed following cleavage of the zymogen precursor plasminogen by host activators tissue plasminogen activator and urokinase.
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The tissue type plasminogen activator antigen concentrations in both oesophageal carcinomas and stomach carcinomas were similar to those of the normal tissues.
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The concentrations of urokinase type plasminogen activator in the duodenum resemble the quantities found in normal stomach tissue biopsy specimens.
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Degradation of fibrin clots is the function of plasmin, a serine protease that circulates as the inactive proenzyme, plasminogen.
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TXA and EACA are lysine analogs that function as competitive inhibitors of plasminogen activation and, at much higher concentrations, noncompetitive inhibitors of plasmin.
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Thrombolytic agents are proteases that convert plasminogen to plasmin, which subsequently lyses clot by breaking down fibrinogen and fibrin.
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Tissue plasminogen activator and, to a lesser degree, urokinase are serine proteases which convert plasminogen to plasmin.
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The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
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All of these agents convert plasminogen to plasmin, which in turn breaks down fibrin and promotes clot lysis.
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Five studies used streptokinase, two used urokinase, and four used tissue plasminogen activator.
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This is performed largely by the enzyme plasmin, generated from its inactive precursor, plasminogen.
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Five studies used streptokinase, two used urokinase, and four used tissue plasminogen activator.
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The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
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The significantly lower plasminogen activator activity of malignant ascites is associated with greatly increased concentrations of plasminogen activator inhibitor-1.
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Robinson and her colleagues measured several blood components involved in clotting, including fats and clotting factors such as plasminogen-activator inhibitor-1 (PAI-1) for the following eight hours.
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Corticosteroid treatment suppressed other proangiogenic factors in hemangioma-derived stem cells, including urokinase plasminogen activator receptor, interleukin-6, monocyte chemoattractant protein 1, and matrix metalloproteinase 1.
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The Borrelia need plasminogen from human blood to migrate to the tick's salivary glands and then infect the human.
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The first is a magnetic nanoparticle designed to target a molecule known as urokinase plasminogen activator receptor.
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It followed 3,339 patients who had been treated for heart attacks with tissue plasminogen activator (Activase), a drug made by Genentech Inc.
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Improved thrombolytic therapy will most likely consist of potent specific plasminogen activators in combination with targeted anticoagulant and/or antiplatelet agents.
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The systematic review included information on three different thrombolytic agents: streptokinase, urokinase, and recombinant tissue plasminogen activator, but direct comparison of different thrombolytic drugs was not possible.
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The experimental pre-clinical treatment involved putting a naturally occurring substance called plasminogen activator inhibitor-1 (PAI-1) into the brains of newborn rats, said Chia-Yi Kuan, M.D.
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Tissue plasminogen activator and, to a lesser degree, urokinase are serine proteases which convert plasminogen to plasmin.
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These results could suggest a prominent role of tissue type plasminogen activator in the pathogenesis of endothelin induced gastric mucosal damage.
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Wu YP, Siao CJ, Lu W, Sung TC, Frohman MA, et al. (2000) The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate.
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As tissue plasminogen activator is manufactured using recombinant biotechnology techniques, it is referred to as rtPA as well as tPA in the study.
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Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
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The concentrations of urokinase type plasminogen activator in the duodenum resemble the quantities found in normal stomach tissue biopsy specimens.
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Urokinase also activates a substance in blood vessels called plasminogen and turns it into plasmin, another protein-destroying enzyme.
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The volunteers 'bodies responded by producing 3 to 5 times as much as normal of a hormone called plasminogen activator inhibitor-1.
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Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
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The fibrinolytic system involves a series of enzymatic reactions that results in the conversion of the proenzyme, plasminogen, into the trypsin-like lyric enzyme, plasmin.
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Urokinase also activates a substance in blood vessels called plasminogen and turns it into plasmin, another protein-destroying enzyme.
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Maybe liver softening-Granules treated hepatic fibrosis by regulating the plasminogen activator system and hasten the fibrin dissolve.
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Plasminogen activators attached to fibrin activate plasminogen, causing the release of the enzyme plasmin within clots and thrombi.
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The amount of colour developed during a fixed time is proportional to the tissue type plasminogen activator activity in the sample.
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Within the fibrinolytic system, plasmin is generated from plasminogen by tissue plasminogen activator, which upon activation lyses fibrin clots.
