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proenzyme

NOUN
  1. any of a group of compounds that are inactive precursors of enzymes and require some change (such as the hydrolysis of a fragment that masks an active enzyme) to become active

How To Use proenzyme In A Sentence

  • All of the serine proteases and the zinc peptidases of pancreatic secretions are produced in the form of their respective proenzymes.
  • Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. WN.com - Articles related to DTI favors zero tariffs on cement, wheat
  • Examples of important proenzymes include pepsinogen, trypsinogen and chymotrypsinogen, which give rise to the proteolytic digestive enzymes.
  • Degradation of fibrin clots is the function of plasmin, a serine protease that circulates as the inactive proenzyme, plasminogen.
  • The next to last step in this chain is the activation of the circulating proenzyme prothrombin into its active form, thrombin.
  • In the case of the serine proteases, they are synthesized as proenzymes, larger molecules that require modification before they become active.
  • These death proteases are part of a proteolytic cascade activating proenzymes into active proteases.
  • Protein digestion begins in the stomach, where a proenzyme called pepsinogen is secreted, autocatalytically converted to Pepsin A, and used for the first step of proteolysis.
  • Examples of important proenzymes include pepsinogen, trypsinogen and chymotrypsinogen, which give rise to the proteolytic digestive enzymes.
  • Trypsin also activates trypsinogen as well as all the other proenzymes in the pancreatic secretion, producing the active proteases and peptidases that hydrolyze dietary polypeptides.
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