How To Use Pyrimidine In A Sentence
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To ensure that there is no interference from the most recent deworming, FECRT should not be performed within eight weeks following the last benzimidazole or pyrimidine treatment, or within 12 (ivermectin) or 16 (moxidectin) weeks after a macrocyclic lactone treatment.
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Consequently, these mutant cells rely exclusively on glycolysis for their energy requirements and require exogenous pyruvate and pyrimidines for growth.
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The ten Light emanations purines a n d cytosine which is a are necessary to preserve the cor - pyrimidine.
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In an attempt to shed light on this matter, we have studied the intrinsic fluorescence properties of the purine and pyrimidine nucleosides dA, dG, dT, and dC in organic solvents in the presence of small amounts of water.
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Multiple mechanisms have evolved to repair damaged DNA, including the versatile nucleotide excision repair (NER) which is capable of removing a variety of bulky helix-distorting lesions, such as UV-induced cyclobutane pyrimidine dimers (CPDs) and 6-4 photoproducts
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Our analyses also suggest that the utilization of products of de novo pyrimidine biosynthesis may differ between different cell types.
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In order to make pyrimidines, the parasite, like other organisms, needs first to make several forms of a vitamin called folic acid.
The Edge of Evolution
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Li S, Waters R (1996) Nucleotide level detection of cyclobutane pyrimidine dimers using oligonucleotides and magnetic beads to facilitate labelling of DNA fragments incised at the dimers and chemical sequencing reference ladders.
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He also studied the orientation of purines and pyrimidines in tobacco mosaic virus and in nucleic acids, by measuring the ultraviolet dichroism of oriented specimens, and he studied, with the visible-light polarizing microscope, the arrangement of virus particles in crystals of TMV and measured dry mass in cells with interference microscopes.
Maurice Wilkins - Biography
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Glutamine is an energy source for enterocytes of the small intestine, helps form nicotinamide for energy transfers and glucosamine for connective tissue, and contributes to purine and pyrimidine nucleotides.
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(A) DNA sequencing gels showing repair of UV-induced cyclobutane pyrimidine dimers (CPDs) in the transcribed strand of the
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The major enzymological studies underway in the field of biochemistry prior to 1950 unfortunately were focused on carbon metabolism, not on amino acid, vitamin, purine, or pyrimidine biosynthesis.
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Breeding a high pyrimidine producting grain is the precondition for producting cytidine and uridine by fermentation.
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The purine and pyrimidine bases in cells are linked to carbohydrate and in this form are termed, nucleosides.
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Two inherited disorders affecting pyrimidine biosynthesis are the result of deficiencies in the bifunctional enzyme catalyzing the last two steps of UMP synthesis, orotate phosphoribosyl transferase and OMP decarboxylase.
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E. Fischer and L. Ach (_Berichte_, 1895, 28, p. 3135) have synthesized it from dimethyl alloxan, whilst W. Traube (_Berichte_, 1900, 33, p. 3435) has obtained it from 1.3 diamethyl 4.5 diamino 2.6 dioxypyrimidine.
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Both of these products involve dimerization of adjacent pyrimidines on the same DNA strand.
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Ticagrelor (BRILINTA (TM)) is an investigational oral antiplatelet treatment for ACS and the first in a new chemical class, the CPTPs (cyclo-pentyl-triazolo-pyrimidines).
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Both purine and pyrimidine bases present similar PI yields at 266 nm.
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The derivatives of purine are called adenine and guanine, and the derivatives of pyrimidine are called thymine, cytosine and uracil.
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The derivatives of purine are called adenine and guanine, and the derivatives of pyrimidine are called thymine, cytosine and uracil.
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Purines and pyrimidines are considered as complex molecules themselves because they are never synthesized as such in vivo.
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NER is the main mechanism used to remove pyrimidine dimers induced by UV cross-linking or chemical damage such as those caused by benzopyrene, aflatoxin, and cisplatin.
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Consequently, these mutant cells rely exclusively on glycolysis for their energy requirements and require exogenous pyruvate and pyrimidines for growth.
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A nitrogenous molecule, either a PYRIMIDINE or a PURINE, that combines with a pentose sugar and phosphoric acid to form a nucleotide, the fundamental unit of nucleic acids.
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D. Sutherland, Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions, Nature 459, 239 (2009). doi: 10.1038/nature08013.
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Consequently, these mutant cells rely exclusively on glycolysis for their energy requirements and require exogenous pyruvate and pyrimidines for growth.
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Some introns also have a sequence rich in pyrimidines that adds up to 10 additional bases at the 3’ end.
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The nucleotides found in cells are derivatives of the heterocyclic highly basic, compounds, purine and pyrimidine.
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Recommended name pyrimidine-deoxynucleoside 2'-dioxygenase Synonyms deoxyuridine
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The chemical and biological effects of UV radiation on purine and pyrimidine nucleosides and nucleotides have been the subject of many studies.
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Webster) obtained an active fraction from yeast and succeeded in separating this into a crystalline basic member belonging to the pyrimidine group which they called _torulin_.
The Vitamine Manual
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The transcription of the operon is coordinately repressed in the presence of excess pyrimidine nucleotides.
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Second, there is no branch in the pyrimidine synthesis pathway.
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Any of several basic compounds derived from or structurally related to pyrimidine, especially the nucleic acid constituents uracil, cytosine, and thymine.
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Furthermore, although Powner and colleagues 'synthetic sequence yields the pyrimidine ribonucleotides, it cannot explain how purine ribonucleotides (which incorporate guanine and adenine) might have formed.
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A nucleotide is a combination of a ribose or deoxyribose sugar, a purine or pyrimidine base, and a phosphate group.
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They form phosphorus-containing organic substances which, together with a form of phosphoric acid, usually contain purine bodies, pyrimidine bodies and a form of sugar or related substance.
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The URA3 gene is essential for yeast pyrimidine biosynthesis.
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Oxidized bases (both pyrimidines and purines) and misincorporated uracil, were similar for fresh and frozen lymphocytes.
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The rearrangement of cross-conjugated mesomeric pyrimidines has been extensively studied.
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Recommended name pyrimidine-deoxynucleoside 2'-dioxygenase Synonyms deoxyuridine
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The derivatives of purine are called adenine and guanine, and the derivatives of pyrimidine are called thymine, cytosine and uracil.
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Of the many difficulties encountered by those in the field, the most frustrating has been the failure to find any way of properly joining the pyrimidine nucleobases — cytosine and uracil — to ribose (Fig. 1a).
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Cooperating with the I.G. Farbenindustry, which supplied the precious raw material for the work, he was able to prove that not an imidazole-ring (as suggested by Jansen and Donath), but a thiazole - and a pyrimidine-ring are present in vitamin
Adolf Windaus - Biography
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CHS, contact hypersensitivity; CPD, cyclobutane pyrimidine dimer;
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Furthermore, although Powner and colleagues 'synthetic sequence yields the pyrimidine ribonucleotides, it cannot explain how purine ribonucleotides (which incorporate guanine and adenine) might have formed.
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Two other ways of recoding the data were cited: eliminating third codon positions and recoding nucleotides as purines and pyrimidines.
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From these results Funk believed the vitamine to belong to a class of substances known as the pyrimidine bases.
The Vitamine Manual
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This is due to an affinity to bind to DNA bases, particularly pyrimidine bases.
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To improve the fit, researchers led by chemical biologist Nathanael Gray, PhD, prepared a group of inhibitors with a different structural scaffold, known as a pyrimidine core, which, it was thought, would mesh more thoroughly.
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Because of the involvement of Polη in promoting error-free replication through cyclobutane pyrimidine dimers, its inactivation in humans causes the variant form of xeroderma pigmentosum, a genetic disorder characterized by a greatly enhanced predisposition to sun induced skin cancers
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Conversely, the reaction of purine and pyrimidine nucleobases with alkylating and oxidizing agents generally results in site-specific cleavage.
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The nitrogenous bases belong to two classes of molecules - purines and pyrimidines.
