How To Use Smooth muscle In A Sentence
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The production of a visceral-specific anti-peptide antibody should permit a further investigation of its expression in smooth muscle cells.
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Pupillary size is controlled by the action of the constrictor and dilator smooth muscles of the iris.
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Chronic idiopathic intestinal pseudoobstruction is usually caused by disease of the enteric nerves or smooth muscle.
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Zhang EY, Stein R, Chang S, Zheng Y, Zderic SA, Wein AJ, Chacko S: Smooth muscle hypertrophy following partial bladder outlet obstruction is associated with overexpression of non-muscle caldesmon.
Publications of the Urology Division
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Current areas of investigation include neurohumoral, cellular and molecular mechanisms regulating airway contractility, airway smooth muscle growth and cell surface receptor expression; regulation of postnatal development and growth of the lung; developmental effects of pulmonary inflammation and oxidative lung injury on airway and pulmonary vascular reactivity; biochemical and molecular regulation of membrane ion channels in cystic fibrosis; maturational changes in chest wall and airway function; pulmonary manifestations of sickle cell disease; the physiological basis of ventilator dependence in children with chronic respiratory insufficiency; and developmental aspects of respiratory mechanics and ventilatory control.
Fellowship Program in Pulmonary Medicine
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Desmin and vinculin are functionally related proteins that are present in the membrane-associated dense bodies in the sarcolemma of the smooth muscle cells.
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The body has many ways to regulate blood pressure: how fast the heart beats; how hard it beats; total blood volume, regulated by total body sodium content as controlled by the kidneys; caliber of arterioles as controlled by smooth muscle in the blood vessel walls.
Archive 2009-04-01
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This would facilitate the calculation of peristaltic velocity and the speed of contractility of gut smooth muscle with high temporal resolution.
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This drug relaxes arteriolar smooth muscle and has been used in the treatment of severe hypertension.
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In addition to its potent vasoconstrictive actions, ET-1 is also a mitogen for vascular smooth muscle cells.
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Also, subjacent vascular smooth muscle cells increase their tonus.
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Like salbutamol, clenbuterol is a Beta2 adrenergic agonist, which relaxes those smooth muscle groups over which you exercise no direct conscious control.
The Explainer: Why clenbuterol?
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Penile smooth muscle is also relaxed by other agents.
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Uterine fibroids are benign tumours developing from the smooth muscles of the uterine wall which can grow at times to as large as 15 cm or more.
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The production of a visceral-specific anti-peptide antibody should permit a further investigation of its expression in smooth muscle cells.
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I wouldn't be surprised if the thin eating champs were born with weak pyloric sphincters, or exhibit higher capacity for smooth muscle relaxation.
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The stromal component, however, typically appears benign and predominantly consists of interlacing bundles of smooth muscle.
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This includes those of the parasympathetic nervous system in the heart, glandular tissue, and smooth muscle.
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Tumor cells also infiltrated the smooth muscle of the ciliary body.
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The parasympathetic nervous system is excitatory and results in the contraction of smooth muscle, whereas the sympathetic system inhibits smooth muscle in the digestive system.
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The dilatory effect of chocolate under resting conditions can be attributed to improved nitric oxide bioavailability, prostacyclin increase, direct effect of chocolate in smooth muscle cells, or activation of central mechanisms," they write.
Grouse Diary Entry
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It turns out that Urelle contains several things, including hyoscyamine: a smooth muscle relaxant.
Archive 2007-09-01
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The center also activates the autonomic motor nerve cells in the cranial nerve nuclei that excite peristalsis in the smooth muscle of the distal esophageal body and relax the lower esophageal sphincter.
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Weak immunoreactivity for NOS2 in the normoxia plus saline group was present in bronchiolar and vascular smooth muscle, bronchiolar epithelium, and Clara cells.
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The second efferent system is the autonomic nervous system, which carries motor information to smooth muscles, cardiac muscle, and various glands.
Neurotoxicity
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This contraction arises from excitation of the circular layer of smooth muscle by autonomic nerves.
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It has been repeatedly reported that smooth muscle antibodies of autoimmune chronic hepatitis are directed to cell actin.
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Two kinds of motor nerves, excitatory nerves that release acetylcholine and inhibitory nerves that release nitric oxide, account for all events that occur in smooth muscle of the esophagus in a swallow.
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This would facilitate the calculation of peristaltic velocity and the speed of contractility of gut smooth muscle with high temporal resolution.
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It also predisposes to thrombosis, leucocyte adhesion, and mural smooth muscle proliferation.
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Several theories of the factors causing smooth muscle cell proliferation have been made.
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He also suggested an expiratory wave of peristaltic smooth muscle contraction starting from the periphery to aid in exhalation.
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Relaxed single smooth muscle cells were obtained by gentle trituration of the digested tissue with a plastic pipette.
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Neither fascicles of smooth muscle cells nor thick-walled tortuous blood vessels were present.
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Grande V, Carelli S, Brancaccio D, et al. (2005) Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angiomyolipoma: EGF is the required growth factor.
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Smooth muscle does not contain troponin and is primarily regulated by the phosphorylation of myosin.
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The antioxidative properties of statins also prevent the development of cardiac and smooth muscle cell hypertrophy.
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Smooth muscle cells possess a contractile apparatus consisting of actin and myosin filaments and the cytoskeleton.
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This tonic contraction is mostly myogenic, due to special properties of this smooth muscle, but it is modified by excitatory and inhibitory nerves.
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This is called the lower esophageal sphincter, which is a thick ring of circular smooth muscle at the point between the esophagus and the stomach.
CreationWiki - Recent changes [en]
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Bitter herbs also tone the smooth muscles in your gastrointestinal tract.
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The mass also contained cystic spaces lined by columnar epithelium, sebaceous glands, cartilage, smooth muscle, and pancreatic acini.
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The esophageal musculature is striated in the proximal esophagus (down to the level of the aortic arch) and is separated by a short transition zone from the smooth muscle portion of the esophagus.
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This increase in water retention, together with contraction of arteriolar smooth muscle and increase in the rate and force of cardiac contraction, results in a rise in blood pressure.
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Objective:To explore the effect of Total Glucosides of Paeony (TGP) on colon smooth muscle of Guinea pig and the regulative function of M receptor on colon motility in vitro.
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: Regional alterations in the expression of smooth muscle myosin isoforms in response to partial bladder outlet obstruction.
Publications of the Urology Division
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This tonic contraction is mostly myogenic, due to special properties of this smooth muscle, but it is modified by excitatory and inhibitory nerves.
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External injury to the alveolar wall may be the counterpart of arteriolar smooth muscle injury.
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Smooth muscle area was determined in 8-m-thick cryostat lung sections.
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“Responses of a Molluscan Smooth Muscle to Acetylcholine and 5-hydroxytryptamine.”
MANUFACTURING DEPRESSION
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Normal epididymis and smooth muscle bundles were present at the edge of the tumor.
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Single stomach smooth muscle cells were isolated by enzymatic dissociation with trypsin and collagenase as described previously.
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Objective: To study the effect of Ailantus Endocuticle on the isolated intestinal smooth muscle of rabbits.
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The placenta produces large amounts of the hormone progesterone, which appropriately prevents the uterine smooth muscle from contracting, but also relaxes smooth muscle throughout the body.
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In addition, localised radiotherapy at the time of stent implantation helps to reduce proliferation of smooth muscle.
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It should be noticed that contraction of the smooth muscles results in relaxation or detumescence.
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They successfully grew skin cells, smooth muscle cells, neurons and other nerve cells known as astrocytes and oligodendrocytes, and pigment producing cells called melanocytes, Reuters reports.
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This smooth muscle is the involuntary sphincter of the posterior urethra in the male.
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Both male and female genitals have smooth muscle tissue that engorges with blood during arousal.
The Science Of Women & Sex
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John Garthwaite had just reported that nitric oxide was a neuro transmitter in the brain, and we wondered whether or not nitric oxide could be the neurotransmitter in the so called nonadrenergic noncholinergic neurons that were known to innervate the corpus cavernosum smooth muscle.
Louis J. Ignarro - Autobiography
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They consist of thin sheets of collagen and smooth muscle with an endothelial covering.
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Endothelial cells and smooth muscle cells of porcine pulmonary trunk were cultured by enzyme-dispersed and substrate-attached explant methods.
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Electrical control activity is caused by the entrainment of the fluctuations of the transmembrane potentials of individual smooth muscle cells.
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Upon the inflation of the alveoli, the lungs release a substance called bradykinin, which causes contraction in smooth muscle and is thought to be partially responsible for contraction of the ductus arteriosus.
CreationWiki - Recent changes [en]
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It is known to form a highly hydrated pericellular coat around chondrocytes, fibrosarcoma, and smooth muscle cells.
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It is possible to isolate a multipotent stem cell from neural crest that can give rise to neurons, glia, and smooth muscle.
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The smooth muscle portion of the esophagus is innervated by neurons within the dorsal motor nucleus of the vagus.
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AIM: To study the effect of fraction F of Naja naja atra venom on proliferation of vascular smooth muscle cells (VSMC).
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Vasodilators, such as acetylcholine and bradykinin, do not exert their effects upon the vascular smooth muscle cell in the absence of the overlying endothelium.
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The results of our study demonstrate that, at dopamine tachyphylaxis of canine tracheal smooth muscle, histamine treatment could recover the contraction to dopamine.
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High potency as an antagonist of 5-HT in isolated smooth muscle preparations was not correlated with high potency as a psychotomimetic.
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Postganglionic parasympathetic nerves mediate both cholinergic contractions and nonadrenergic, noncholinergic relaxations of smooth muscle in the airway.
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Isoprenaline exerts its effects by relaxing the smooth muscle tissues lining the finely branched tubular network of bronchioles that surround the lungs.
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Pulmonary vascular smooth muscle cell is an important executor of vasoconstriction and a key contributor of pulmonary vascular structure remodeling.
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The airways (trachea, bronchi, bronchioles) are surrounded by a type of involuntary muscle known as smooth muscle.
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The production of a visceral-specific anti-peptide antibody should permit a further investigation of its expression in smooth muscle cells.
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These authors found ultrastructural evidence of altered endothelial and smooth muscle cells within chorionic vessels exhibiting HEV-like lesions.
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Histopathology shows degeneration of the smooth muscle with fibrosis.
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We measured the tracheal smooth muscle reactivity to methacholine.
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Anticholinergics block muscarinic receptors on airway smooth muscle and possibly on submucosal gland cells.
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In writing the 1955 review on the "Pharmacology of vascular smooth muscle," I had become very interested in the mechanisms by which sympathetic postganglionic denervation and certain drugs like cocaine markedly potentiate the response of effector organs to epinephrine and norepinephrine, yet markedly reduce the response to the sympathomimetic tyramine.
Robert F. Furchgott - Autobiography
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The force of contraction declines slightly as it advances, reaching a nadir at about the level where the muscle becomes smooth muscle.
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Sodium is important for maintaining blood volume, it works in concert with potassium, which is needed for vasodilatation or constriction, and it also interacts with calcium, which is needed for vascular smooth muscle tone.
Kristin Wartman: Change in Season: Why Salt Doesn't Deserve Its Bad Rap
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Blood vessels only work when both endothelia and vascular smooth muscle are bound together.
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The areola contains softer and darker skin tissue which surrounds the nipple and which also contains smooth muscle fibers.
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Shukla AR, Nguyen T, Zheng Y, Zderic SA, DiSanto M, Wein AJ, Chacko S: Over expression of smooth muscle specific caldesmon by transfection and intermittent agonist induced contrac-tion alters cellular morphology and restores differentiated smooth muscle phenotype.
Publications of the Urology Division
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Current areas of investigation include neurohumoral, cellular and molecular mechanisms regulating airway contractility, airway smooth muscle growth and cell surface receptor expression; regulation of postnatal development and growth of the lung; developmental effects of pulmonary inflammation and oxidative lung injury on airway and pulmonary vascular reactivity; biochemical and molecular regulation of membrane ion channels in cystic fibrosis; maturational changes in chest wall and airway function; pulmonary manifestations of sickle cell disease; the physiological basis of ventilator dependence in children with chronic respiratory insufficiency; and developmental aspects of respiratory mechanics and ventilatory control.
Fellowship Program in Pulmonary Medicine
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When thought to involve abnormalities of smooth muscle without abnormalities in myenteric neurons the syndrome is termed hollow visceral myopathy.
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Ultrastructurally, GIST is similar to ICC and be deficiency of smooth muscle or nervous feature.
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Current research suggests that, during the final stages of wound healing, myofibroblasts, again, generally identified by [alpha] smooth muscle actin expression, die through apoptosis to leave an acellular scar.
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Thus, our measurements appear to be particularly well suited for characterization of dynamic actin rheology during airway smooth muscle contraction.
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The cells grow adherently and exhibit myoblast morphology, possessing many of the properties characteristic of smooth muscle cells.
Undefined
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Products of complement activation cause smooth muscle contraction and increased vascular permeability and induce degranulation of phagocytic cells, mast cells, and basophils.
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There is mucous metaplasia, enlargement of the mass of bronchiolar smooth muscle, and loss of alveolar attachments.
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This causes damage to collagen and elastin, loss of smooth muscle cells and increased amounts of basophilic ground substance in the medial (elastic) layer of the aorta.
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Like salbutamol, clenbuterol is a Beta2 adrenergic agonist, which relaxes those smooth muscle groups over which you exercise no direct conscious control.
The Explainer: Why clenbuterol?
-
Electrical control activity is caused by the entrainment of the fluctuations of the transmembrane potentials of individual smooth muscle cells.
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The airways (trachea, bronchi, bronchioles) are surrounded by a type of involuntary muscle known as smooth muscle.
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Their action relies upon inhibiting the passage of calcium ions (electrically charged calcium atoms) into the smooth muscle walls.
Lower Your Blood Pressure in 4 Easy Stages
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These are involved in regulating vasculogenesis and angiogenesis after ischemic injury, interactions of cells with adhesive proteins and blood vessels, proliferation of smooth muscle cells during atherogenesis, metabolism of lipoproteins and non-thrombogenic characteristics of endothelial cells
PLoS ONE Alerts: New Articles
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Blood vessel dilation is due to blockage of calcium channels in smooth muscle cells or inhibition of sodium-calcium ion exchange.
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A relaxation of cervical smooth muscle facilitates dilation.
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The myometrium is a thick coat containing smooth muscle and abundant connective tissues.
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The difficulty of predicting the biological behavior of uterine smooth muscle tumors has been recognized for many years.
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The efflux of potassium ions hyperpolarizes the cell membrane, resulting in vascular smooth muscle relaxation.
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Nitric oxide also inhibits proliferation of smooth muscles, reduces leukocyte adhesiveness, and regulates endothelial permeability, to lipoproteins and other constituents of plasma.
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Morphologically, these granular cells resemble the true cells of myoblastoma and have been shown to be altered smooth muscle cells.
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The profile parallels that observed for bradykinin stimulated smooth muscle cells.
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Nitroglycerin causes relaxation of vascular smooth muscle in both arteries and veins, although the effect on veins predominates at low doses.
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The results of our study demonstrate that, at dopamine tachyphylaxis of canine tracheal smooth muscle, histamine treatment could recover the contraction to dopamine.
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A portion of the cystic mass showed benign bladder smooth muscle and serosa focally adhered to the outer cyst wall.
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It has been repeatedly reported that smooth muscle antibodies of autoimmune chronic hepatitis are directed to cell actin.
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Some veins do not possess smooth muscle fibers and, as a result, do not have a tunica media.
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In laboratory studies using human airway smooth muscle cells, they found that combined treatment with estradiol and the beta-agonist, isoproterenol (which non-selectively activates both beta-1 and beta-2 adrenergic receptors), had a synergistic effect on decreasing intracellular calcium and force more than either estradiol or isoproterenol alone.
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Deeper in the airway wall there is cartilage and smooth muscle.
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In large part, moving food along the alimentary tract is a matter of smooth muscle functioning, and Pavlov decided to investigate the byssus retractor, the smooth muscle that Mytilus edulis, the common mussel, uses to close its shell.
MANUFACTURING DEPRESSION
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Context.-Interstitial cells of Cajal are pacemaker cells in the smooth muscles of the gut.
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Recently, evidence that glyceryl trinitrate's relaxant effect on uterine smooth muscle may be enhanced during pregnancy has raised interest in its use.
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Carmichael et al. hypothesized that oxytocin is involved in orgasmic muscle contractions, because of its classical function in smooth muscle contractions during parturition and for milk ejection.
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The accumulating cells are either macrophages or smooth muscle cells.
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Smooth muscle fibers usually contract slowly but are capable of sustained contractile activity.
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The inhaled bronchodilators relieve only the airway narrowing from spasm of the bronchial smooth muscle.
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Unphosphorylated, attached cross-bridges in tonic mammalian smooth muscle have a very slow rate of release of ADP.
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It remains to be shown that W512 is uniquely sensitive to nucleotide binding and hydrolysis in smooth muscle myosin.
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Second, the tumor showed dual differentiation into a classic granulosa cell component with different patterns and a central component in which there was mesenchymal differentiation into smooth muscle and osteoid components.
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This smooth muscle is the involuntary sphincter of the posterior urethra in the male.
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Smooth muscles are involuntary and located inside internal organs such as the stomach and intestines.
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A microvillous tegument was appreciated overlying a thin layer of smooth muscle and a single row of stromal cells.
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However, as with bronchial smooth muscle hypertrophy, it can be expected that the remodeled vessels may exhibit altered reactivity to contractile or relaxant agents.
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Esophageal peristalsis can also be excited reflexly in the smooth muscle segment (but not in the striated muscle part), by transient distension of the organ, both in situ and in vitro.
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Large continuous masses of eosinophils were situated within the extracellular matrix, beneath the bronchiolar smooth muscle layer.
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Mannikarottu AS, Disanto ME, Zderic SA, Wein AJ, Chacko S.: Altered expression of thin filament-associated proteins in hypertrophied urinary bladder smooth muscle.
Publications of the Urology Division
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Two of the isolated smooth muscle preparations that I unsuccessfully tested for bioassay of VEM and VDM were a helically-cut strip of rabbit aorta, which responded with contraction to epinephrine, and a longitudinal segment of rabbit duodenum, which exhibited spontaneous rhythmic contractions that were inhibited by epinephrine and stimulated by acetylcholine.
Robert F. Furchgott - Autobiography
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The hemorrhoidectomy specimens showed a stroma of connective tissue containing many blood vessels, and interwoven bundles of smooth muscle.
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On the other hand, melatonin reportedly induced contraction of bovine bronchial smooth muscle.
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The L-arginine-NO system exerts various biological actions including vascular smooth muscle relaxation and inhibition of platelet aggregation.
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Associated with the follicle are sebaceous glands and the arrector pili smooth muscle fiber bundle.
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They successfully grew skin cells, smooth muscle cells, neurons and other nerve cells known as astrocytes and oligodendrocytes, and pigment producing cells called melanocytes, Reuters reports.
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Smooth muscles are involuntary and located inside internal organs such as the stomach and intestines.
