How To Use Trophoblast In A Sentence
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In a healthy pregnancy, cells that come from the embryo's placenta-called trophoblast cells-move into the walls of the uterus and help to open up maternal arteries, thereby increasing the available blood and nutrient supply.
Slate Articles
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The placenta derives from embryonic cells called trophoblasts, which form a ball around the cells that ultimately develop into the fetus.
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Human cytotrophoblast cells were collected from the placentas and cultured.
Signs of the Times
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Microscopic examination demonstrated hydropic degenerated villi with a circumferential trophoblastic cell proliferation and moderate atypia, consistent with a complete hydatidiform mole.
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The outer trophoblast cells of the released blastocyst begin to invade the epithelium, burrowing into the underlying endometrial stroma.
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But living animal was produced only if the sheep blastomer was taken from trophoblast, the structure giving rise to placenta and extraembryonic fetal membranes, and goat cells from inner mass of embrionic stem cells.
On Thursday, the Legg report will be published along with...
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When the developing, fertilized egg at the ‘blastocyst’ stage becomes implanted in the lining of the uterus, it develops ‘villi’ - fine, frond-like cellular projections from its outermost layer, the trophoblast.
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Hyperglycosylated hCG inhibits apoptosis in extravillous invasive cytotrophoblast cells promoting cell invasion, growth and malignancy.
BioMed Central - Latest articles
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AIM To isolate cytotrophoblasts from human placentae and investigate the specific route of mother to infant transmission of hepatitis C virus (HCV).
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Perhaps they're hoping the the terms "trophoblast", "blastocoel", and "blastocyst" will disguise the fact that we're talking about a human being?
Archive 2004-06-01
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The derivation of HESC cultures requires the removal of the trophoblast.
ANNIES CHASE
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Perhaps they're hoping the the terms "trophoblast", "blastocoel", and "blastocyst" will disguise the fact that we're talking about a human being?
A Doctor's Perspective on Stem Cell Research
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In addition to allowing regeneration of syncytiotrophoblast and investigating chronic regulation of apoptosis and autophagy, another reason for us to incubate villous explants and cytotrophoblastic cells under normoxia or HR for 48 hours before administration of vitamins C and E is to precondition the trophoblast cells with our experimental settings.
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Johnson MP, Childs MD, Isada NB, Koppitch III GC, Evans MI: Trisomy 16 CVS and viable pregnancy: Lethal aneuploidy compartmentalized to the trophoblast in two otherwise normal pregnancies.
Prenatal Diagnosis
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The surface of the sphere is made up of a layer of specialized cells called the trophoblast.
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After treatment in the HR condition, cytotrophoblast cells were lysed in a cold RIPA buffer (Pierce Biotechnology) containing a protease inhibitor cocktail (Roche).
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Indeed, degeneration of the syncytiotrophoblast is noted in third-trimester explants after 8 hours of culture; however, a newly formed trophoblast layer is found by 48 hours
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In most of these diseases, the diagnosis can be made by genetic analysis of cultured trophoblast cells derived from CVS.
In Utero Stem Cell Transplantation
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The vessels of the villus are surrounded by a thin layer of mesoderm consisting of gelatinous connective tissue, which is covered by two strata of ectodermal cells derived from the trophoblast: the deeper stratum, next the mesodermic tissue, represents the cytotrophoblast or layer of Langhans; the superficial, in contact with the maternal blood, the syncytiotrophoblast (Figs. 36 and 37).
I. Embryology. 11. Development of the Fetal Membranes and Placenta
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The vessels of the villus are surrounded by a thin layer of mesoderm consisting of gelatinous connective tissue, which is covered by two strata of ectodermal cells derived from the trophoblast: the deeper stratum, next the mesodermic tissue, represents the cytotrophoblast or layer of Langhans; the superficial, in contact with the maternal blood, the syncytiotrophoblast (Figs. 36 and 37).
I. Embryology. 11. Development of the Fetal Membranes and Placenta
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In a 2009 French study at the University of Caen, scientists discovered that glyphosate can kill the cells in the outer layer of the human placenta (the trophoblast membrane), which in turn can kill the placenta.
Jeffrey Smith: Genetically Modified Soy Diets Lead to Ovary and Uterus Changes in Rats
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trophoblastic cancer
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The trophoblast eventually forms the placenta, through which the embryo proper receives dissolved nutrients and is cleansed of waste.
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The endothelial lining of the uterine vessels ceases at the point where they terminate in the intervillous space which is lined by the syncytiotrophoblast.
I. Embryology. 11. Development of the Fetal Membranes and Placenta
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Researchers analyzed trophoblast cells from the placenta from 40 pregnant women about to undergo surgery for ectopic pregnancy, miscarriage or abortion.
Getting Closer to the Root of What Causes Baldness
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The cells of the trophoblast become differentiated into two strata: an outer, termed the syncytium or syncytiotrophoblast, so named because it consists of a layer of protoplasm studded with nuclei, but showing no evidence of subdivision into cells; and an inner layer, the cytotrophoblast or layer of Langhans, in which the cell outlines are defined.
I. Embryology. 5. Segmentation of the Fertilized Ovum
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Such a change in the prevailing oxygen concentration may lead to a difference in the susceptibility of cytotrophoblasts and syncytiotrophoblast for women with preeclampsia in comparison to those who have healthy pregnancies
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Sibley CP, Jones CJ, Turner MA, Greenwood SL (2001) The functional regeneration of syncytiotrophoblast in cultured explants of term placenta.
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This variant is an autocrine factor, acting on extravillous invasive cytotrophoblast cells to initiate and control invasion as occurs at implantation of pregnancy and the establishment of hemochorial placentation, and malignancy as occurs in invasive hydatidiform mole and choriocarcinoma.
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The pathologist determines the histologic diagnosis of the trophoblastic disease, most importantly , if choriocarcinoma is present.
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You had mentioned that twins can develop when the inner cell mass splits in the blastocyst and forms two embryos enclosed in a common trophoblast.
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They confirmed that explant cultures with a longer incubation period are valuable for studying the death and repair of the trophoblast and for investigating the chronic regulation of placental function under pathological conditions.
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Digital images from ten randomly selected fields that provided a minimum of 500 nuclei within the trophoblast layer (syncytiotrophoblast and cytotrophoblasts) for each section were saved.
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after implantation of the blastocyst in the uterine wall the trophoblast divides into two layers, the chorion and the placenta
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The blastocyst is a sphere made up of an outer layer of cells (the trophoblast), a fluid-filled cavity (the blastocoel), and a cluster of cells on the interior (the inner cell mass).
Think Progress » FACT CHECK: Snow’s False and Misleading History of Stem Cell Research
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A villus has a fibromuscular core with fetal blood vessels and is covered by an epithelium termed the trophoblast.
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The cells of the trophoblast become differentiated into two strata: an outer, termed the syncytium or syncytiotrophoblast, so named because it consists of a layer of protoplasm studded with nuclei, but showing no evidence of subdivision into cells; and an inner layer, the cytotrophoblast or layer of Langhans, in which the cell outlines are defined.
I. Embryology. 5. Segmentation of the Fertilized Ovum
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Results Clusters of malignant trophoblast appeared to be arising from residual normal chorionic villi with projection into the intervillous space in the infarct area of placenta.
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Using term villous cytotrophoblast preparations, Aris and colleagues found that high levels of vitamins C (50 and 100 µM) and E (20 and 50 µM) affect placental function and immunity in standard culture conditions, as reflected by a decreased secretion of hCG and an increased production of TNF-alpha in a dose-dependent manner
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While regular hCG is made by fused villous syncytiotrophoblast cells, extravillous invasive cytotrophoblast cells make the variant hyperglycosylated hCG.
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Caveat: Technical difficulties plus contamination of some uterine samples prevented collection of trophoblast cells from every patient.
Getting Closer to the Root of What Causes Baldness
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The vascular endothelium was destroyed by villous proliferation and trophoblastic invasion in this vessel.
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Objective: To study the expression of the small subunit ribonucleotide reductase(R2) in gestational trophoblastic diseases (GTD) and to assess its prognostic value.
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The trophoblast is made up of an internal layer of cubical or prismatic cells, the cytotrophoblast or layer of Langhans, and an external layer of richly nucleated protoplasm devoid of cell boundaries, the syncytiotrophoblast.
I. Embryology. 11. Development of the Fetal Membranes and Placenta
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Multiple gestation, gestational trophoblastic disease, triploidy, trisomy 21 syndrome, and hydrops fetalis have been associated with an increased incidence of hyperemesis gravidarum.
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In some instances, multiple tissues from individual specimen were analyzed, including amniotic membrane, chorionic membrane, chorionic villous stroma, and trophoblast, as well as fetal tissues.
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Using term villous cytotrophoblast preparations, Aris and colleagues found that high levels of vitamins C (50 and 100 µM) and E (20 and 50 µM) affect placental function and immunity in standard culture conditions, as reflected by a decreased secretion of hCG and an increased production of TNF-alpha in a dose-dependent manner
PLoS ONE Alerts: New Articles
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Molar pregnancies (also called gestational trophoblastic disease and hydatidiform mole) happen when the cells that are supposed to develop into the placenta instead develop into a tumor made of trophoblastic (placental) cells.
Our Bodies, Ourselves: Pregnancy and Birth
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Unlike the hydatidiform moles, choriocarcinomas and placental-site trophoblastic tumors lack chorionic villi.
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In one experiment scientists harvested a subpopulation of non-trophoblastic placental cells, grew them up, and seeded them on to a polymer scaffold.
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The cells of the trophoblast become differentiated into two strata: an outer, termed the syncytium or syncytiotrophoblast, so named because it consists of a layer of protoplasm studded with nuclei, but showing no evidence of subdivision into cells; and an inner layer, the cytotrophoblast or layer of Langhans, in which the cell outlines are defined.
I. Embryology. 5. Segmentation of the Fertilized Ovum
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It has been demonstrated that isolated cytotrophoblasts from preeclampsia or fetal growth restriction and their derived syncytiotrophoblast are more sensitive to apoptosis compared with those from normal pregnancies
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Objective To evaluate treatment and clinical prognosis of gestational trophoblastic tumor ( GTT ) patients with bladder metastasis.
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A typical day-5 human embryo consists of 200-250 cells, most of which comprise the trophoblast, which is the outermost layer of the blastocyst.
ANNIES CHASE
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They have not usually been described as totipotent because, the inner cell mass having already differentiated from trophoblast, the cells of the inner cell mass were believed to be no longer able to give rise to the cells of the trophoblast.
CreationWiki - Recent changes [en]
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The trophoblast is made up of an internal layer of cubical or prismatic cells, the cytotrophoblast or layer of Langhans, and an external layer of richly nucleated protoplasm devoid of cell boundaries, the syncytiotrophoblast.
I. Embryology. 11. Development of the Fetal Membranes and Placenta
