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tumor suppressor gene

NOUN
  1. a suppressor gene that blocks unscheduled cell division

How To Use tumor suppressor gene In A Sentence

  • These observations suggest that the mutated tyrosine phosphatases are tumor suppressor genes, regulating cellular pathways that may be amenable to therapeutic intervention.
  • Neurofibromatosis type 1 is a common autosomal dominant disorder with a high rate of penetrance. It is caused by the mutation of the tumor suppressor gene NF1, which encodes neurofibromin.
  • In contrast, the chapter on cancer cytogenetics essentially assumes that the reader possesses an understanding of the concepts of oncogenes and tumor suppressor genes and their applications in cytogenetics.
  • P 53 gene is found in human tumors so far the most relevant tumor suppressor gene.
  • However, they point out that several genes, including potential oncogenes and tumor suppressor genes, failed to revert to never-smoker levels even after 30 years of cessation.
  • Tumor suppressor genes play a key role in the regulation of cell growth.
  • The genes found to undergo genetic alterations in cancer have been placed into two categories: oncogenes and tumor suppressor genes.
  • Tumor suppressor genes are located on autosomal chromosomes.
  • Objective To study the relationship between tumor suppressor gene PTEN , P 16, P 15 and primary cervical carcinomas.
  • If those mutations happen to be in oncogenes or tumor suppressor genes and they accumulate over time, it might cause a skin cancer to develop.
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