How To Use antimetabolite In A Sentence
- Methotrexate is an antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases. PLoS ONE Alerts: New Articles
- The class of anticancer drugs that has been developed to interfere with aspects of nucleotide metabolism is known as the antimetabolites.
- With the latter therapy, once patients are weaned from steroids, the purine antimetabolite is continued for an indefinite period while the physician monitors white blood cell count and liver enzymes.
- This suggested that other enzymes might also recognize such a side chain as a pentose and that nucleoside analogs of this kind might have antimetabolite properties. Nobel Lecture The Purine Path To Chemotherapy
- In 1940, Woods and Fildes (1,2) had put forth the antimetabolite theory to explain the action of sulfonamides on bacteria, suggesting that the sulfonamides interfered with the utilization of a necessary nutrient, para-aminobenzoic acid. Nobel Lecture The Purine Path To Chemotherapy
- Antimetabolite: Substance that competes with, replaces, or inhibits a specific compound within a cell, whose functioning is thereby disrupted.
- Contributors Mary Relling did pharmacological studies of antimetabolites and identified their relation with risk of brain tumour.
- Therefore, acyclovir is transformed into its corresponding nucleotide which is the active antimetabolite and the growth of the virus is inhibited (Figure 3). Physiology or Medicine 1988 - Press Release
- Learn about the research that led to the use of the antimetabolite drugs 6-mercaptopurine The Spark of Yahoo!
- Most forms of gout can be treated by administering the antimetabolite, allopurinol.
